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干燥综合征(Sgren’s Syndrome,SS)是一种以侵犯泪腺、唾液腺等外分泌腺体为主的慢性自身免疫性疾病,主要是由于自身免疫的过度应答反应,造成外分泌腺体大量淋巴细胞、浆细胞浸润,使腺体细胞遭到破坏、功能丧失,从而出现一系列临床症状与表现,其发病可能与病毒感染、遗传和性激素异常等多种因素有关,在这些因素的共同作用下,机体免疫异常,组织损伤。与该病关系较密切的病毒有EB病毒、巨细胞病毒、丙型肝炎病毒等。
Sjogren’s Syndrome (SS) is a chronic autoimmune disease mainly affecting exocrine glands such as the lacrimal gland and salivary gland. It is mainly caused by an over-response of autoimmune diseases, resulting in a large number of exocrine glandular lymphocytes, Plasma cell infiltration, so that glandular cells were destroyed, loss of function, resulting in a series of clinical symptoms and manifestations, the incidence may be related to viral infection, genetic and sex hormone abnormalities and other factors related to the combination of these factors, the body Immune disorders, tissue damage. Viruses associated with the disease are EB virus, cytomegalovirus, hepatitis C virus and so on.