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目的观察小儿复方氨基酸和锌联合治疗小儿难治性腹泻疾病的临床效果。方法将小儿难治性腹泻患儿76例,根据就诊次序分为观察组与对照组各38例。对照组采用常规对症治疗方案,观察组在常规治疗方案中加入小儿复方氨基酸和锌联合治疗。治疗2周后比较2组患儿的临床有效率、止泻时间及脱水纠正时间。结果观察组患儿临床总有效率为92.11%显著高于对照组的71.05%,差异有统计学意义(P<0.05)。且治疗期间2组患儿均未见明显的不良反应。观察组的止泻时间、脱水纠正时间均明显短于对照组,差异有统计学意义(P<0.05)。结论小儿复方氨基酸和锌联合治疗小儿难治性腹泻疾病在提高临床疗效的同时能较快缓解患儿的临床症状,且无明显不良反应,值得临床借鉴和采纳。
Objective To observe the clinical effect of combined treatment of pediatric combined amino acids and zinc on refractory diarrhea in children. Methods 76 cases of children with intractable diarrhea were divided into observation group and control group according to the order of treatment of 38 cases. The control group was treated with routine symptomatic treatment, and the observation group was treated with the combined treatment of pediatric combined amino acids and zinc in routine treatment. After 2 weeks of treatment, the clinical efficacy, diarrhea time and dehydration correction time in two groups were compared. Results The total clinical effective rate in observation group was 92.11%, which was significantly higher than that in control group (71.05%), the difference was statistically significant (P <0.05). There were no obvious adverse reactions in both groups during treatment. The observation group’s diarrhea time, dehydration correction time were significantly shorter than the control group, the difference was statistically significant (P <0.05). Conclusion Combined treatment of pediatric combined amino acids and zinc in children with refractory diarrhea can improve the clinical curative effect and alleviate the clinical symptoms in children without obvious adverse reactions, which is worthy of clinical reference and adoption.