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目的探讨胰腺癌患者术后发生腹腔感染的相关危险因素,以期为临床防治提供思路。方法回顾性分析本院2010年1月-2014年12月连续318例行根治手术治疗的胰腺癌患者的临床资料。将患者按术后是否发生腹腔感染分为感染组(19例)和对照组(299例),对两组患者的一般资料、术中情况、术后并发症等相关危险因素进行分析。结果所有患者均顺利完成手术,腹腔感染19例,感染率5.97%(19/318),无因腹腔感染死亡患者。多因素分析结果显示,患者术中输血及术后发生胰瘘、胆瘘是术后腹腔感染的独立危险因素(P<0.05)。结论胰腺癌患者术中输血、术后发生胰瘘及胆瘘是术后腹腔感染的主要危险因素。
Objective To investigate the related risk factors of postoperative abdominal infection in patients with pancreatic cancer so as to provide ideas for clinical prevention and treatment. Methods The clinical data of 318 consecutive patients undergoing radical surgery from January 2010 to December 2014 in our hospital were retrospectively analyzed. The patients were divided into infection group (n = 19) and control group (n = 299) according to whether postoperative abdominal infection occurred. The general data, intraoperative status, postoperative complications and other related risk factors of the two groups were analyzed. Results All the patients were successfully performed surgery, 19 cases of abdominal infection, the infection rate was 5.97% (19/318), no death due to abdominal infection. The results of multivariate analysis showed that transfusion of blood and postoperative pancreatic fistula occurred during operation, and biliary fistula was an independent risk factor of postoperative abdominal infection (P <0.05). Conclusion Intraoperative blood transfusion, postoperative pancreatic fistula and biliary fistula are the main risk factors of postoperative abdominal infection.