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目的:了解药品不良反应(ADR)发生的特点、规律及易发原因,为临床预防ADR和合理用药提供参考。方法:对某院2010～2011年上报的157例不良反应报告进行分析。结果:157例药品不良反应报告中,以抗菌药居多,占40.76%;引起ADR最主要的给药方法为静脉滴注,占72.61%;ADR最常见的临床表现为皮肤及其附件损害,占43.95%。结论:应重视ADR的报告和监测工作,加强临床合理用药监管,以减少和避免ADR的发生。
Objective: To understand the characteristics, regularity and causes of adverse drug reaction (ADR) and provide reference for clinical prevention of ADR and rational drug use. Methods: A hospital reported from 2010 to 2011, 157 cases of adverse reactions were analyzed. Results: 157 cases of adverse drug reactions reported to antibacterial drugs, accounting for 40.76%; ADR caused by the main method of intravenous infusion, accounting for 72.61%; ADR most common clinical manifestations of skin and its attachment damage, accounting for 43.95%. Conclusion: Pay attention to the report and monitoring of ADR and strengthen the supervision of clinical rational drug use to reduce and avoid the occurrence of ADR.