目的:观察卡前列素氨三丁醇预防产后出血的疗效.方法:167例有发生产后出血高危因素的患者为研究对象,随机分为试验组和对照组.试验组于胎儿娩出后应用卡前列素氨丁三醇250单位(1支),对照组常规使用缩宫素,分别记录两组研究对象产后2小时阴道出血量、产后24小时阴道出血量、产后5天血红蛋白计数、产后出血的发生率.结果:产后2小时出血量实验组比对照组减少平均126.90ml,产后24小时出血量实验组比对照组减少75.03ml,产后5天血红蛋白试验组比对照组大于5.50g.两组患者的产后出血发生率为3.65%及11.65%,差异有显著性(P<0.01).结论:卡前列素氨三丁醇针用于预防产后出血有显著疗效.“,”objective: to observe the effect of Carboprost Tromethamine Injection in the treatment of postpartum hemorrhage. Methods: to select 167 patients with high risk factors of postpartum hemorrhage as the research object and divide them into experimental group and control group randomly. The experimental group were given 250 units of Carboprost Tromethamine Injection after fetal childbirth, the control group were given normal oxytocin, to record the vaginal hemorrhage of 2 hours after delivery ; 24 hours after delivery; to record the hemoglobin count and the incidence of postpartum hemorrhage. Results: the hemorrhage volume in experimental group 2 hours after delivery was 126.90ml lessthan that in the control group. The hemorrhage volume in experimental group was 75.03 ml less than that in the control group 24 hours after delivery, hemoglobin in experimental group was 5.50g more than that in the control group 5 days after delivery, the postpartum hemorrhage rates of the two groups were 3.65% and 11.65%,the difference is significant(P<0.01).Conclusion:Carboprost Tromethamine Injection is effective to prevent postpartum hemorrhage.