妊娠急性脂肪肝(AFLP)是发生于妊娠晚期的一种严重并发症,肝细胞在短时间内大量快速脂肪变性。主要表现为黄疸、凝血功能障碍和肝功能急剧衰竭,同时容易累及到肾脏。AFLP的发生可能与肝脏线粒体脂肪酸氧化功能障碍有关,探讨AFLP的发病机制并研究其诊治手段,能够降低孕产妇病死率。 Acute fatty liver of pregnancy (AFLP) is a serious complication that occurs in the third trimester of pregnancy, and hepatocytes rapidly massively rapidly degenerate in a short period of time. Mainly for jaundice, coagulation disorders and rapid failure of liver function, while easily involving the kidneys. The occurrence of AFLP may be related to dysfunction of liver mitochondrial fatty acid oxidation, to explore the pathogenesis of AFLP and study its diagnosis and treatment methods, can reduce maternal mortality.