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Eur Heart J,2009,30(22):2749-2757.生长分化因子15(GDF-15)是与转化生长因子β相关的细胞因子,通过多种压力调节途径,在心肌细胞表达增加,可以预测经药物治疗的心力衰竭患者的死亡风险。该研究旨在确定GDF-15是否能预测心脏再同步化治疗(CRT)后的死亡率和发病率。方法和结果:
Eur Heart J, 2009, 30 (22): 2749-2757. GDF-15 is a cytokine that is associated with transforming growth factor beta and can be predicted by increased expression in cardiomyocytes via various stress-regulating pathways Risk of death from medically treated patients with heart failure. The aim of this study was to determine whether GDF-15 predicts mortality and morbidity after cardiac resynchronization therapy (CRT). Method and result: