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2-氯吡啶是合成吡硫霉净(2-巯基吡啶-N-氧化物钠)和其他防霉防腐剂的中间体。国内尚无产品供应。我们曾以2-氨基吡啶为原料,用Sandmeyer和Gattermann反应分别合成2-氯吡啶和2-溴吡啶,但收率极低。
2-Chloropyridine is an intermediate for the synthesis of pyrimethamine (sodium 2-mercaptopyridine-N-oxide) and other mold preservatives. There is no domestic product supply. We have 2-aminopyridine as raw materials, Sandmeyer and Gattermann reaction were synthesized 2-chloropyridine and 2-bromopyridine, but the yield is very low.