论文部分内容阅读
目的:分析川渝地区石油单位工作人员健康体检中肺部结节检出情况，为石油单位工作人员早期肺癌筛查提供依据。方法:于2021年1月，回顾性收集2020年川渝地区健康体检中完成胸部低剂量螺旋CT (LDCT）的6 002名石油单位工作人员为研究对象，收集其影像学及临床资料，采用χn 2检验分析不同性别、年龄和工种间石油单位工作人员肺结节和疑似肺癌肺结节检出率的差异。n 结果:6 002名研究对象中，男性3 853名（64.2%），女性2 149名（35.8%），平均年龄（47.25±12.13）岁；共检出肺结节431例（7.2%），疑似肺癌肺结节57例（0.9%），随访行手术治疗45例，术后病理确诊肺癌41例（91.1%）。不同年龄组间研究对象肺结节和疑似肺癌肺结节检出率差异均有统计学意义（χn 2=51.23、18.81，n P<0.001）；年龄51~60岁组和≥61岁组研究对象肺结节检出率高于年龄≤40岁组和41~50岁组，年龄≥ 61岁组研究对象疑似肺癌肺结节检出率高于年龄≤40岁组、41~50岁组和51~60岁组，石油工人疑似肺癌肺结节检出率高于普通职工（n P<0. 05）。女性石油工人的肺结节检出率高于普通工人（χn 2＝8. 09，n P＝0. 004）；年龄≥61岁石油工人肺结节检出率高于普通工人（χn 2＝37. 94，n P<0. 001）。男性石油工人疑似肺癌肺结节检出率高于普通工人（χn 2＝8. 42，n P＝0. 004）；年龄51~60岁和≥61岁石油工人疑似肺癌肺结节检出率均高于普通工人（χn 2=4.70、8.74，n P=0.030、0.003）。n 结论:LDCT适用于石油单位工作人员早期肺癌筛查，在临床筛查过程中，对于年龄≥51岁的石油工人应将LDCT作为常规体检项目。“,”Objective:To provide scientific evidence for early lung cancer screening, to analyze the incidence of pulmonary nodules among petroleum company staffs in Sichuan-Chongqing Area.Methods:In January 2021 , 6002 petroleum company staffs in Sichuan-Chongqing Area which scanned by low-dose spiral computed tomography (LDCT) of chest in medical examination center in 2020 were retrospectively collected as objects. Their imaging and clinical data were collected. χ n 2 test was used to analyze the differences in the detection rates of lung nodules and suspected lung cancer nodules among workers in petroleum company staffs of different genders, ages and types of work.n Results:Among the 6002 objects, 3853 (64.2%) were male and 2149 (35.8%) were female, with an average age of (47.25±12.13) years old. A total of 431 cases (7.2%) of pulmonary nodules and 57 cases (0.9%) of suspected lung cancer nodules were detected. 45 cases were followed up with surgical treatment, and 41 cases (91.1%) of lung cancer were diagnosed by postoperative pathology. There were significant differences in the detection rates of pulmonary nodules and suspected lung cancer nodules between different age groups (χn 2=51.23, 18.81 , n P<0.001). The detection rates of pulmonary nodules in the age groups 51-60 years old and ≥61 years old were higher than those in the age groups≤40 years old and 41-50 years old (n P<0.05). The detection rate of suspected lung cancer nodules in the age group≥ 61 years old was higher than those in the age groups≤40 years old, 41-50 years old and 51-60 years old (n P< 0.05) . And the detection rate of suspected lung cancer pulmonary nodules in oil workers was higher than that of ordinary workers (n P<0.05) . Among female objects, the detection rate of pulmonary nodules in oil workers was higher than that in ordinary workers (χn 2=8.09, n P=0.004) . The detection rate of pulmonary nodules in oil workers aged ≥61 years old was higher than ordinary workers (χn 2=37.94, n P<0.001) . Among male objects, the detection rate of suspected lung cancer pulmonary nodules in oil workers was higher than that in ordinary workers (χn 2=8.42, n P=0.004) . The detection rates of suspected lung cancer pulmonary nodules in oil workers aged 51-60 years old and ≥61 years old groups were higher than those of ordinary workers (χn 2=4.70, 8.74; n P=0.030, 0.003) .n Conclusion:LDCT is suitable for early lung cancer screening for petroleum company staffs. During the clinical screening process, LDCT should be used as a routine physical examination item for petroleum workers older than 51 years old.