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目的了解安仁县中小学教师HBV感染状况,为防治提供依据。方法对安仁县2004年在岗3 686名中小学教师进行现况调查,采血标本用ELISA法检测乙型肝炎表面抗原(HBsAg),对HBsAg阳性者采用ELISA法检测抗-HBs,HBeAg,抗-HBe,抗-HBc四项HBV感染标志。用SPSS12.0统计软件包建立数据库,对结果进行χ2检验分析。结果安仁县中小学教师HBsAg阳性率为17.58%,其中男性(20.28%)高于女性(13.26%),不同性别HBsAg阳性率差异有显著性(χ2=29.709,P<0.01)。各年龄组HBsAg阳性率差异无显著性(χ2=3.693,P>0.05)。不同类别教师HBsAg阳性率差异有显著性(χ2=8.851,P<0.05),不同区域教师HBsAg阳性率差异有显著性(χ2=13.760,P<0.01)。648例HBsAg阳性者中抗-HBe、抗-HBc均阳性者占70.37%;HBsAg阳性者中HBeAg、抗-HBc均阳性者占12.19%。结论安仁县中小学教师HBsAg阳性率高,属高发人群,乡镇和乡村教师高于县城教师。在教师队伍中加强对乙型肝炎的防治措施实属必要。
Objective To understand the HBV infection status of primary and secondary school teachers in Anren County and provide basis for prevention and treatment. Methods The current status of 3 686 primary and secondary school teachers in Anren County was investigated in 2004. Blood samples were collected to detect HBsAg by ELISA and anti-HBs, , Anti-HBc four signs of HBV infection. With SPSS12.0 statistical software package to establish a database, the results of χ2 test analysis. Results The positive rate of HBsAg in primary and secondary school teachers in Anren County was 17.58%. The prevalence of HBsAg was significantly higher in males (20.28%) than in females (χ2 = 29.709, P <0.01). There was no significant difference in HBsAg positive rate among all age groups (χ2 = 3.693, P> 0.05). The positive rates of HBsAg in different categories of teachers were significantly different (χ2 = 8.851, P <0.05). The positive rates of HBsAg in different regions were significantly different (χ2 = 13.760, P <0.01). Among 648 HBsAg positive individuals, 70.37% were positive for anti-HBe and anti-HBc while 12.8% of HBsAg positive were positive for HBeAg and anti-HBc. Conclusions Primary and secondary school teachers in Anren County have a high positive rate of HBsAg, which is a high incidence population. Teachers in township and village are higher than county teachers. It is necessary to strengthen the prevention and treatment of hepatitis B in the teaching staff.