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目的观察氟康唑注射液与制霉菌素粉剂在治疗外耳道真菌病的临床疗效。方法将76例外耳道真菌病患者随机分成对照组和治疗组。治疗组49例给予0.2%氟康唑氯化钠注射液外耳道灌洗治疗,对照组27例给予制霉菌素粉剂外耳道喷洒治疗,2周后观察疗效。结果在临床疗效方面,治疗组有效率为87.76%,对照组有效率为66.67%,两组间比较差异有统计学意义(χ2=9.054,P=0.025)。结论 0.2%氟康唑氯化钠注射液既能有效杀灭外耳道病菌,临床操作又简单,且易为患者接受,值得临床推广应用。
Objective To observe the clinical efficacy of fluconazole injection and nystatin powder in the treatment of external auditory canal fungal disease. Methods 76 cases of external auditory canal fungal disease were randomly divided into control group and treatment group. In the treatment group, 49 cases were given 0.2% fluconazole sodium chloride injection external auditory canal irrigation, while 27 cases in the control group were treated with nystatin powder external ear canal spray treatment. The therapeutic effect was observed after 2 weeks. Results The clinical curative effect was 87.76% in the treatment group and 66.67% in the control group. The difference between the two groups was statistically significant (χ2 = 9.054, P = 0.025). Conclusion 0.2% fluconazole sodium chloride injection can effectively kill the pathogenic bacteria of the external auditory canal, the clinical operation is simple, and easy for patients to accept, worthy of clinical application.