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目的了解学龄前儿童乙肝病毒感染状况及乙肝疫苗的免疫效果。方法采集静脉血,检测抗-HBs。结果随年龄增长抗-HBs阳性率而呈现逐年下降的趋势。2008年儿童与前2 a相比,抗-HBs阳性率有所下降。常住儿童与流动儿童相比,乙肝疫苗合格接种率、抗-HBs阳性率差异均有统计学意义(P<0.05)。结论对入托儿童应定期开展检测,适时进行加强免疫。加强对流动儿童的管理,提高流动儿童的乙肝疫苗合格接种率。
Objective To understand the status of hepatitis B virus infection in pre-school children and the immune effect of hepatitis B vaccine. Methods Venous blood was collected for detection of anti-HBs. The results showed that the positive rate of anti-HBs with age showed a downward trend year by year. Children in 2008 compared with the previous 2 a, anti-HBs positive rate decreased. Compared with the floating children, the eligible vaccination rate of hepatitis B vaccine and the positive rate of anti-HBs in resident children were statistically significant (P <0.05). Conclusion Children should be checked regularly to carry out tests to strengthen the timely immunization. Strengthen the management of migrant children and improve the eligible vaccination rate of migrant children with hepatitis B vaccine.