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(接8月下)3.3使用其他血管扩张剂与尼可地尔的治疗相结合有机硝酸盐类首先扩张静脉系统而不是微动脉。相反地,尼可地尔能够通过达到静脉系统和动脉血管扩张平衡来产生最佳的效果,减轻系统血管阻力。因此,由于硝酸盐类的应用,某种情况下诱导了低血压。在现阶段研究中,我们使用三硝酸甘油酯导致了低血压。另一方面,尼可地尔能够在相对低BP患者中给药,因此与卡培立肽联合使用是安全的。卡培立肽在尼可地尔组中应用于14位患者
(Next August) 3.3 Combined Use of Other Vasodilators and Nicorandil Treatment Organic nitrates first expanded the venous system rather than the arterioles. In contrast, nicorandil produces the best results by reducing the balance between the venous system and the arterial vasodilation system, reducing systemic vascular resistance. Therefore, in some cases, hypotension is induced due to the use of nitrates. In the current study, we used triglyceride to cause hypotension. Nicorandil, on the other hand, can be administered in patients with relatively low BP and is therefore safe to use in combination with capecitabine. Capecitabine was administered to 14 patients in the nicorandil group