人们最初在关节内注药时发现可的松类的增白皮肤作用,后来发现外用可的松也有作用,这一作用还可用以测定经皮吸收制剂的作用强度,现已逐步成为此类制剂的生物利用度的一种常规研究方法,具有无损伤、简便低廉,重复性好的优点。作者研究了用三维色度法测定此类霜剂的皮肤增白作用。 People initially found in the joint injection of cortisone whitening skin, and later found that there is also the role of cortisone, this effect can also be used to determine the strength of the percutaneous absorption of agents, has now gradually become such agents The bioavailability of a conventional research methods, with no damage, simple and cheap, good repeatability advantages. The authors studied the skin whitening effect of such creams by three-dimensional colorimetry.