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目的:评价我国医学文献中上消化道出血防治性研究随机对照实验的质量,了解其能否为临床实践提供可靠的决策依据。方法:对我国可能刊登上述随机对照实验(RCT)的5种消化病学期刊进行人工检索,并根据国际循证医学标准对其中的RCT报道进行分析。结果:查阅杂志544期,共含论著23781篇,检出RCT报告46篇,并从研究对象的选择,样本含量,随机方法,组间可比性,实验措施,对照措施,盲法,疗效评价指标,干预措施临床效果,随访及失访问题等几个方面进行分析。结论:我国目前上消化道出血防治性研究RCT数量,尚不能满足临床实践的需要。
Objective: To evaluate the quality of randomized controlled trials in the prevention and treatment of upper gastrointestinal bleeding in Chinese medical literature and to find out whether it can provide a reliable basis for clinical practice. METHODS: Five Chinese journal of digestive diseases, which may publish the above randomized controlled trials (RCTs), were searched by hand and analyzed according to the international evidence-based medical standards. Results: A total of 23781 articles were published in the journal, including a total of 23781 articles. Forty-six RCT reports were detected. The results of the study included 46 samples of RCT, sample size, randomization, comparability among groups, experimental measures, control measures, , Clinical effects of interventions, follow-up and loss of follow-up and other aspects of the analysis. Conclusion: At present, the quantity of RCT in prevention and treatment of upper gastrointestinal bleeding in our country still can not meet the needs of clinical practice.