目的　对单纯人畜扩大化疗 (策略 1)与人畜扩大化疗辅以易感地带灭螺 (策略 2 )这 2种防治策略控制湖沼型垸内亚型血吸虫病的流行进行 3年的成本 -效果对比研究 ,以期找出经济、有效的防治对策。方法　计算策略 1与策略 2的防治成本与效果。结果　 3年累计成本 -效果比为 :策略2是策略 1的 2 .13倍。策略 1的人群感染率下降 40 % ,仍维持在 11% -12 %之间 ,无抗洪涝能力。策略 2的人群感染率持续下降。在 3年中 ,策略 2使人群感染率下降了 89.2 % ,使耕牛感染率下降了73 .8% ,使有螺面积下降了 93 .7% ,使活螺密度感染率下降了 99.7%。结论　策略 1成本虽低 ,但效果不理想。策略 2能达到基本控制的目的 ,其防治成本有逐年下降趋势 OBJECTIVE: To compare the cost-effectiveness of three strategies for controlling the epidemic of subtype schistosomiasis in lakeshore between two strategies of expanding chemotherapy alone (strategy 1) and enlarged human and animal treatment combined with susceptible zone snail (strategy 2) , With a view to find an economical and effective prevention and control measures. Methods to calculate the cost and effect of strategy 1 and strategy 2. Results The 3-year cumulative cost-effectiveness ratio is: Strategy 2 is 2.13 times of Strategy 1. Strategy 1, the population infection rate decreased 40%, still maintained at between 11% -12%, no anti-flood capacity. Strategy 2 population infection rates continued to decline. In 3 years, strategy 2 reduced the infection rate of the population by 89.2%, decreased the infection rate of cattle by 73.8%, decreased the snail area by 93.7% and caused the live snail infection rate to drop by 99.7%. Conclusion Strategy 1 low cost, but the effect is not satisfactory. Strategy 2 can achieve the purpose of basic control, the prevention and control costs have declined year by year