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目的:探讨Luminal A型与Luminal B型乳腺癌临床病理与超声特征的差异。方法:回顾性分析本院乳腺中心经病理及免疫组化证实97例Luminal A型和54例Luminal B型乳腺癌患者资料,对比分析其临床病理特征与超声学表现。结果:Luminal A型和Luminal B型临床病理特征在组织学分级(P=0.007)及淋巴结转移率(P=0.027),超声学表现在边界(P=0.039)、微钙化(P=0.016)及血流分级(P=0.011)差异有统计学意义。与Luminal A型比较,Luminal B型乳腺癌具有组织学分化低、淋巴结转移率较高、超声学边界不清,微钙化明显、血供丰富等特征。结论:Luminal A型与Luminal B型在临床病理和超声学特征存在一定的差异,对预后的评估及治疗方案的制订有一定的指导作用。
Objective: To investigate the differences of clinicopathological and ultrasonic features between Luminal A and Luminal B breast cancers. Methods: The clinical data of 97 patients with Luminal A and 54 patients with Luminal B breast cancer confirmed by pathology and immunohistochemistry were retrospectively analyzed. The clinicopathological characteristics and ultrasound findings were compared. Results: The clinicopathological features of Luminal A and Luminal B in histological grade (P = 0.007) and lymph node metastasis (P = 0.027) were significantly different between borderline (P = 0.039), microcalcifications Blood flow classification (P = 0.011) was statistically significant. Compared with Luminal A type, Luminal B breast cancer has the characteristics of low histological differentiation, higher lymph node metastasis, unclear boundary of ultrasound, micro-calcification and rich blood supply. Conclusion: There are some differences in clinical pathology and ultrasound features between Luminal A type and Luminal B type, which may guide the evaluation of prognosis and the formulation of treatment regimen.