随着日常饮食的欧美化和社会年龄构成的老龄化,日本人胆石的发生率比战前约增加了4倍。胆道感染常合并胆石症,由于胆石症增多,而成为临床上的一种常见病。胆道感染包括胆囊炎、胆管炎、肝脓肿和胆汁性腹膜炎等,其中胆囊炎和胆管炎往往合并发生。其病程大致可分为急性和慢性两种。 细菌感染和胆汁淤滞是引起胆道感染的两个必要条件,因此,治疗胆道感染最重要的就是解除胆汁淤滞和进行药物治疗,而在药物治疗中尤为重要的是选择适当的化学制剂。 近年来,化学制剂日新月异,强力抗生素相继问世,但胆汁中的菌属也发生了改变,弱致病菌的感染率增加。另外,随着细菌培养技术的进步,发现厌氧菌经常成为致病菌,这是治疗上的重要问题。 随着各种图像诊断和内镜治疗等方法的进展, With the aging of the European diet and the social age of the daily diet, the incidence of Japanese gallstones increased about four times over the pre-war period. Biliary tract infection often associated with cholelithiasis, due to an increase of cholelithiasis, and become a common clinical disease. Biliary tract infections include cholecystitis, cholangitis, liver abscess and biliary peritonitis, etc., of which cholecystitis and cholangitis often occur together. The course can be divided into acute and chronic two. Bacterial infections and cholestasis are two prerequisites for causing biliary tract infections. Therefore, the most important treatment for biliary tract infections is to relieve cholestasis and drug therapy, and it is especially important in medical treatment to select the appropriate chemical. In recent years, with the ever-changing chemical agents, powerful antibiotics have come out, but the bile bacteria have also changed, the infection rate of weak pathogens increased. In addition, with the progress of bacterial culture technology, it has been found that anaerobic bacteria often become pathogens, which is an important therapeutic issue. With a variety of image diagnosis and endoscopic treatment methods such as the progress,