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探讨儿童分化型甲状腺癌的临床特征和治疗特点。方法 回顾分析经手术治疗的18岁以下的分化型甲状腺癌32例的临床资料。结果 32例患者中男8例，女24例。发病年龄＜14岁11例，≥ 14岁21例；累及双侧甲状腺19例，单侧13例。多发病灶23例，单发病灶9例；肿瘤≥1 cm 30例，＜1 cm 2例；病理证实甲状腺乳头状癌27例，甲状腺滤泡状癌5例；发生颈淋巴结转移25例，转移率为78.13%，颈部Ⅰ~Ⅵ区及上纵隔区均有淋巴结转移，各区转移率分别为 3.13%、31.25%、31.25%、37.50%、9.38%、68.75%、25.00%；发生甲状腺外侵12例，肺转移5例，甲状腺癌术后颈部淋巴结转移10例。随访1~14年，无死亡病例。结论 儿童分化型甲状腺癌具有侵袭性强、转移率高、复发率高、死亡率低的临床特点，甲状腺全切除术和规范的颈结清扫术值得高度重视。
To investigate the clinical features and treatment characteristics of differentiated thyroid cancer in children. Methods The clinical data of 32 patients with differentiated thyroid carcinoma below the age of 18 who were treated surgically were retrospectively analyzed. Results There were 8 males and 24 females in 32 patients. The age of onset was less than 14 years old in 11 cases and ≥ 14 years old in 21 cases. There were 19 bilateral thyroid patients and 13 unilateral patients. Multiple lesions in 23 cases, single lesions in 9 cases; tumors ≥ 1 cm in 30 cases, <1 cm in 2 cases; pathologically confirmed papillary thyroid carcinoma in 27 cases, 5 cases of thyroid follicular carcinoma; 25 cases of cervical lymph node metastasis, metastasis rate At 78.13%, lymph node metastasis was found in the cervical lymph nodes I-VI and upper mediastinum. The metastases in each zone were 3.13%, 31.25%, 31.25%, 37.50%, 9.38%, 68.75%, 25.00%, respectively; Cases, 5 cases of lung metastasis, 10 cases of cervical lymph node metastasis after thyroid cancer. Follow-up 1 to 14 years, no deaths. Conclusion Children’s differentiated thyroid cancer has the characteristics of strong invasiveness, high metastasis rate, high recurrence rate and low mortality. Total thyroidectomy and standard neck dissection are highly valued.