体重及骨峰值对骨质疏松诊断的影响

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股骨颈骨密度目前已经成为诊断骨质疏松的金指标。世界卫生组织(WHO)建议骨质疏松的诊断标准为骨密度T值小于-2.5个标准差(SD)。由于这一诊断标准在全世界各地普遍造成误诊与漏诊现象,所以在过去的十几年里,世界各地都在调整自身的当地诊断标准。但这种当地化的标准并没有改善骨质疏松诊断中存在的误诊及漏诊现状。本文分析了个体间骨峰值的差异(54.3%),并讨论了体重与骨峰值的相关性(0.97)。股骨颈骨强度分析的结果是,尽管个体间骨密度峰值差别很大,但股骨颈能支撑体重的倍数(抗骨折能力)却都比较接近(11.9±1.5).因此骨密度或其T值只能说明受试者骨量的多少,不能说明骨质疏松的程度。本文对44例受试者的测试结果、临床症状、及问诊资料进行了综合分析,确诊有7名骨质疏松病人。根据骨密度的T值在44名受试者中共诊断出5名骨质疏松病人,这5名中有3名在上述7名病人之列(确诊),另外2名属于将正常人误诊为骨质疏松(误诊),共漏诊了4名骨质疏松病人(漏诊)。被误诊的受试者体重较轻(小于62千克),而被漏诊的病人体重较重(大于74千克).临床上依据骨密度T值诊断骨质疏松容易将骨骼正常且体重较轻的受试者误诊为骨质疏松病人,而将已经患有骨质疏松且体重较大的病人漏诊。 Femoral neck bone mineral density has now become the gold index in the diagnosis of osteoporosis. According to the World Health Organization (WHO), the diagnostic criteria for osteoporosis is that the T value of bone mineral density is less than -2.5 standard deviations (SD). Because of the widespread misdiagnosis and misdiagnosis of this diagnostic standard throughout the world, local diagnostic standards have been adapted around the world for more than a decade. However, this localized standard does not improve the current misdiagnosis and missed diagnosis in the diagnosis of osteoporosis. This article analyzes the differences in interbody spikes (54.3%) and discusses the correlation between body weight and bone spikes (0.97). The results of femoral neck bone strength analysis showed that although the difference in peak BMD among individuals was very large, the multiple of the femoral neck support body weight (anti-fracture ability) was relatively close (11.9 ± 1.5) .Body density or its T value Can explain how much of the subject’s bone mass, can not explain the degree of osteoporosis. In this paper, 44 subjects were test results, clinical symptoms, and medical information were analyzed, diagnosed with 7 osteoporosis patients. Five osteoporosis patients were diagnosed in 44 subjects according to the T value of BMD. Three of the five patients were diagnosed as having the above seven patients (diagnosed), and the other two belonged to patients who misdiagnosed as normal Quality loose (misdiagnosed), a total of missed four osteoporosis patients (missed diagnosis). Subjects who were misdiagnosed were underweight (less than 62 kg) and those who were missed were heavier (more than 74 kg). Clinically, diagnosis of osteoporosis based on the T value of bone mineral density is likely to result in normal and less-severe bones The patient was misdiagnosed as an osteoporotic patient, while a patient who already had osteoporosis and a heavier weight was misdiagnosed.
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