多发性骨髓瘤是一种原发于骨髓并伴有高球蛋白血症(hypergammaglobulinemia)和异常浆细胞增生的恶性疾病。多见于老年人,80％在40～70岁之间,40岁以下者很少见。临床表现有局部疼痛、骨骼破坏、病理性骨折、神经症状、贫血、出血和肾脏的损害。近年来发病率有逐渐增加的趋势。多发性骨髓瘤的特征为浆细胞异常增生, Multiple myeloma is a malignant disease of primary bone marrow associated with hypergammaglobulinemia and abnormal plasma cell proliferation. More common in the elderly, 80% of 40 to 70 years of age, 40 years of age are rare. Clinical manifestations of local pain, bone destruction, pathological fractures, neurological symptoms, anemia, bleeding and kidney damage. In recent years, the incidence has gradually increased. Multiple myeloma is characterized by abnormal proliferation of plasma cells,