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目的:比较序贯疗法与标准三联疗法根除幽门螺杆菌(Hp)的临床疗效。方法:选自我院门诊2013年8月-2014年6月期间所收治的58例幽门螺杆菌阳性消化性溃疡患者,依据来院就诊顺序单双号将其分为实验组与参照组,各29例。实验组患者给予序贯疗法,参照组患者给予标准三联疗法,比较两组患者的Hp根除率、不良反应以及成本-效果比。结果:实验组Hp根除率高于参照组,P<0.05;实验组成本-效果比优于参照组,P<0.05;两组患者的不良反应比较无显著差异,P>0.05。结论:在幽门螺杆菌的根除治疗中,序贯疗法较于标准三联疗法根除效果更为显著,且可为患者节省医疗费用,具有较高的临床实践价值。
Objective: To compare the clinical efficacy of sequential therapy and standard triple therapy in the eradication of Helicobacter pylori (Hp). Methods: Fifty-eight patients with H. pylori-positive peptic ulcer were selected from outpatient clinics in our hospital from August 2013 to June 2014. The patients were divided into experimental group and reference group . Patients in the experimental group were given sequential therapy and patients in the reference group were given standard triple therapy. Hp eradication rates, adverse reactions, and cost-effectiveness were compared between the two groups. Results: The Hp eradication rate in the experimental group was higher than that in the reference group (P <0.05). The cost-effectiveness ratio of the experimental group was better than that of the reference group (P <0.05). There was no significant difference in adverse reactions between the two groups (P> 0.05). Conclusion: Sequential therapy is more effective than standard triple therapy in the treatment of Helicobacter pylori eradication, and can save patients medical costs and has high clinical value.