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目的研究乳酸菌阴道胶囊在妊娠晚期未足月胎膜早破中的预防作用。方法选取2014年2月-2015年11月在该院接受治疗的83例妊娠晚期未足月产妇的病例资料进行分析。按照随机法将83例产妇分为空白对照组(41例)和乳酸菌预防组(42例)。空白对照组未给予用药,乳酸菌预防组睡前清洗外阴后于阴道后穹窿处放置乳酸菌阴道胶囊进行预防性用药。观察:(1)阴道清洁度、乳酸菌阳性率;(2)胎膜早破发生率;(3)干预前后产妇阴道p H水平的变化。结果乳酸菌预防组阴道清洁度、乳酸菌阳性率较空白对照组高(P<0.05);乳酸菌预防组胎膜早破发生率比低于空白对照组低(P<0.05);治疗前两组阴道p H水平相似(P>0.05),治疗后乳酸菌预防组阴道p H水平明显改善,差异有统计学意义(P<0.05)。结论妊娠晚期未足月胎膜早破产妇应用乳酸菌阴道胶囊可有效促进阴道内环境的改善,提升乳酸菌阳性率,降低胎膜早破发生率,改善母婴结局。
Objective To study the preventive effect of lactic acid bacteria vaginal capsule in preterm premature rupture of membranes. Methods The data of 83 pregnant women with preterm third trimester who were treated in our hospital from February 2014 to November 2015 were analyzed. According to the randomized method, 83 pregnant women were divided into blank control group (41 cases) and lactic acid bacteria prevention group (42 cases). The blank control group was not given medication, lactic acid bacteria prevention group before and after cleaning the vulva at the vaginal fornix placed lactic acid bacteria vaginal capsules for preventive medication. Observe: (1) vaginal cleanliness, the positive rate of lactic acid bacteria; (2) the incidence of premature rupture of membranes; (3) before and after maternal vaginal p H level changes. Results The vaginal cleanliness and the positive rate of lactic acid bacteria in lactic acid bacteria prevention group were higher than those in blank control group (P <0.05). The incidence of premature rupture of membranes was lower in lactic acid bacteria prevention group than in control group (P <0.05) H levels were similar (P> 0.05). After treatment, vaginal p H level in lactobacilli prevention group was significantly improved, the difference was statistically significant (P <0.05). Conclusion The application of lactic acid bacteria vaginal capsule in preterm premature rupture of membranes can effectively improve the vaginal environment, increase the positive rate of lactic acid bacteria, reduce the incidence of premature rupture of membranes and improve the outcome of maternal and infant.