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目的了解2009-02发生在陕西省汉中市,以西乡县为主要区域的一起儿童“不明原因肺炎”疫情的病因。方法建立病例定义,采用统一的流行病学个案调查表对病例进行调查,描述流行特征,采集患儿咽拭子标本进行病原学检测。结果 2009-01/02,汉中市共计发生儿童“不明原因肺炎”病例32例,发病高峰为1月下旬,病例主要为农村儿童,占病例的81.25%;临床表现为持续发热伴咳嗽、肺部出现影像学改变,无死亡病例。PCR检测证实为腺病毒感染,对PCR阳性产物进行序列测定和分析,确定为腺病毒7型。结论发生在汉中市以西乡县为主要区域的儿童“不明原因肺炎”疫情是由腺病毒7型感染为主引起的儿童肺炎局部流行。
Objective To understand the etiopathogenisis of children with unexplained pneumonia in 2009-02 in Hanzhong City, Shaanxi Province and Xixiang County as the main area. Methods The definition of the case was established, the case was investigated by a unified epidemiological case questionnaire, the epidemiological characteristics were described, and the throat swab specimens of children were collected for etiological detection. Results A total of 32 cases of children with “unexplained pneumonia” were found in Hanzhong City from January 2009 to February 2009 with peak incidence of late January and 81.25% of cases. The clinical manifestations were persistent fever with cough, Imaging changes in the lungs, no deaths. PCR test confirmed that adenovirus infection, PCR-positive products were sequenced and analyzed, identified as adenovirus type 7. Conclusions Children with “unexplained pneumonia” in Xixiang County, Hanzhong City, are endemic to children with pneumonia caused by adenovirus type 7 infection.