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应用骨髓移植治疗再生障碍性贫血和急性白血病日益普遍。骨髓移植的主要并发症是移植物抗宿主病(GVHD)。此病被认为是免疫介导的供者免疫活性细胞和受者细胞所显示的不同抗原之间相互作用的结果。GVHD的急性型累及淋巴系统、皮肤、肝脏和胃肠道。大多数骨髓移植物的受者发生急性GVHD。在某些病人该型是暂时性的,
The application of bone marrow transplantation for the treatment of aplastic anemia and acute leukemia is increasingly common. The main complication of bone marrow transplantation is graft versus host disease (GVHD). The disease is thought to be the result of an immune-mediated interaction between donor immunocompetent cells and different antigens displayed by recipient cells. The acute form of GVHD involves the lymphatic system, the skin, the liver, and the gastrointestinal tract. Acute GVHD occurs in recipients of most bone marrow grafts. In some patients this type is temporary,