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目的:了解广东省手足口病病例密切接触者和健康人群肠道病毒带毒状况。方法:选取广东省珠三角和非珠三角两个地区手足口病病例密切接触者及健康人群作为调查对象,采集标本进行病原学检测,对结果进行统计分析。结果:密切接触者和健康人群之间EV71(P<0.05)、CoxA16(P<0.01)各自的阳性率差异有统计意义;珠三角和非珠三角两地区密切接触者EV(P<0.05)、CoxA16(P<0.05)以及两地区健康人群EV(P<0.01)各自的阳性率差异有统计意义。结论:广东省手足口病病例密切接触者EV71和Cox-A16感染率高于健康人群;健康人群以携带非EV71非CoxA16肠道病毒为主。
Objective: To understand the status of enterovirus infection in close contacts and healthy population of HFMD cases in Guangdong Province. Methods: The close contacts of HFMD patients and healthy population in two areas of Pearl River Delta and non-Pearl River Delta of Guangdong Province were selected as the investigation objects. The specimens were collected for etiological detection and the results were statistically analyzed. Results: The positive rates of EV71 (P <0.05) and CoxA16 (P <0.01) between the close contact and the healthy population were statistically significant. The close contacts EV between the PRD and non-Pearl River Delta (P <0.05) The positive rates of CoxA16 (P <0.05) and EV (P <0.01) of healthy people in the two regions were statistically different. Conclusion: The prevalence of EV71 and Cox-A16 in close contact with HFMD cases in Guangdong Province is higher than that in healthy population. The healthy population is predominantly non-EV71 non-CoxA16 enterovirus.