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目的研究老年胃癌患者肿瘤相关性贫血(CRA)发生情况,探讨其相关影响因素,为改善患者的预后提供依据。方法 2013年11月—2014年6月,选取英山县中医医院268例老年胃癌患者作为研究对象,采用美国国立肿瘤研究所贫血分级标准,营养评价采用微型营养评价精法。结果 268名老年胃癌患者发生CRA 145人(54.10%),平均血红蛋白值为(91.64±18.78)g/L,不同性别老年胃癌患者年龄差异无统计学意义(P>0.05);不同年龄段老年胃癌患者CRA发生率差异有统计学意义(P<0.05);发生CRA组与未发生CRA组微型营养评价精法得分差异有统计学意义(P<0.05);影响老年胃癌患者CRA发生的因素有手术方式,化疗,病理分期和放疗(均P<0.05)。结论老年胃癌患者贫血发生率较高,与患者的年龄,营养状态,手术方式,抗肿瘤治疗,病理分期密切相关。
Objective To study the incidence of tumor-associated anemia (CRA) in elderly patients with gastric cancer and to explore its related factors to provide evidence for improving the prognosis of patients. Methods From November 2013 to June 2014, 268 elder patients with gastric cancer were enrolled in the study. The anemia grading standards of the National Institute of Cancer were used. The nutrition evaluation was based on the micro-nutrition evaluation method. Results A total of 268 elderly patients with GCA had a CRA of 145 (54.10%) and an average hemoglobin value of (91.64 ± 18.78) g / L. There was no significant difference in the age of gastric cancer among different sexes (P> 0.05) There was significant difference in the incidence of CRA between the CRA group and the CRA group (P <0.05). There was significant difference between the CRA group and the CRA group (P <0.05). The factors influencing the incidence of CRA in elderly patients with gastric cancer were surgery Methods, chemotherapy, pathological staging and radiotherapy (all P <0.05). Conclusion The incidence of anemia in elderly patients with gastric cancer is high, which is closely related to the patient’s age, nutritional status, operation mode, anti-tumor therapy and pathological stage.