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肾移植是治疗慢性肾衰竭患者的最理想疗法。然而,肾移植术后早期急性排斥反应(AR)往往是导致移植物失功的重要因素,严重降低人、肾存活率。研究显示,使用免疫诱导治疗可显著减少AR的发生率。一、抗体免疫诱导剂在肾移植中的应用回顾诱导治疗通常是指在肾移植术前或术后短期之内应用生物免疫抑制剂加强对患者免疫系统的抑制,以阻断或减轻排斥反应的发生。
Kidney transplantation is the best treatment for patients with chronic renal failure. However, early acute rejection (AR) after kidney transplantation is often an important factor leading to graft failure, which seriously reduces human and renal survival. Studies have shown that the use of immune-induced therapy can significantly reduce the incidence of AR. First, the antibody immunosuppressive agents in renal transplantation review Induction therapy usually refers to the application of bio-immunosuppressive agents before or shortly after renal transplantation to enhance the inhibition of the patient’s immune system to block or reduce rejection occur.