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目的 评价铅对作业女工子代健康的影响。方法 以某冶炼厂职工学校 94名小学生(6~ 10岁 ,其母亲孕前至调查时从事铅作业 )作为接触组 ;以无铅污染的农村小学 94名学生作对照。两组年龄、性别、年级、家庭情况基本相近。用原子吸收光谱仪测定血铅 ;电感耦合等离子光谱仪测定发中的铅、锌、铜和镉 ;用荧光仪测定锌卟啉 ;用WHO推荐的神经行为核心测试组合 (NCTB)测定神经行为功能 ;用高压液相色谱仪、电化学仪测定尿中高香草酸 (HVA)、香草扁桃酸 (VMA)。所有数据用SPSS软件作t检验。结果 两组身高、体重、胸围差异无显著性 (P >0 .0 5 ) ;血铅、血锌卟啉、血色素、红细胞总数和尿中HVA、VMA等指标两组差别有非常显著性 (P <0 .0 1)。行为功能数字跨度 (顺序 )得分 ,接触组低于对照组 (P <0 .0 5 ) ,简单反应时最快值、数字跨度总和及数字跨度 (倒序 )得分接触组低于对照组 (P <0 .0 1)。发铅、发锌、发铜和发镉接触组高于对照组 (P <0 .0 1)。结论 铅对作业女工子代健康有不良影响。
Objective To evaluate the effect of lead on the health of working women workers. Methods A total of 94 primary school students (6 ~ 10 years old, whose mothers were pregnant before the survey) were included in the study as lead group and 94 students from rural elementary school with lead-free pollution as controls. Two groups of age, gender, grade, family situation are similar. Determination of lead, zinc, copper and cadmium in hair with an inductively coupled plasma spectrometer; Determination of zinc porphyrin by fluorimetry; Determination of neurobehavioral function using the Neurobehavioral Core Test Set (NCTB) recommended by the WHO; High pressure liquid chromatography and electrochemistry were used to measure HVA and VMA in urine. All data were t test with SPSS software. Results There was no significant difference in height, weight and chest between the two groups (P> 0.05). There were significant differences between the two groups in blood lead, porphyrin, hemoglobin, red blood cell count and urine HVA and VMA <0 .0 1). The score of behavioral function was higher in the contact group than in the control group (P <0.05), the fastest value in simple response, the sum of the number of spans and the number of spans in the reverse order (P < 0 .0 1). Hair lead, hair zinc, hair copper and hair cadmium exposure group was higher than the control group (P <0.01). Conclusion Lead adversely affects the health of working women workers.