本文孪生之长子具典型的猫叫综合征的临床表现,次子表型正常。外周血淋巴细胞染色体G显带分析显示,本双胎都为5P~-和正常细胞的嵌合核型。染色体多态比较分析发现,两个正常细胞和异常细胞分属同一细胞系;手皮纹分析二者亦不具一致性。因此,作者认为多本双胎为异卵双生,外周血染色体出现的嵌合现象,可能系在胚胎期发生了造血细胞互换所致。 The twin eldest son with a typical cat called syndrome clinical manifestations, the second sub-phenotype is normal. Peripheral blood lymphocyte chromosome G banding analysis showed that the twins are 5P ~ - and normal cells chimeric karyotype. Chromosome polymorphism comparative analysis found that two normal cells and abnormal cells belong to the same cell line; hand pattern analysis of the two are not consistent. Therefore, the authors believe that many twins are fraternal twins, chimerism in peripheral blood chromosomes may be due to embryonic hematopoietic cell exchange.