目的 观察思他宁治疗肝硬化门静脉高压食管胃底曲张静脉破裂大出血的效果,并与垂体后叶素进行比较。方法 将40例肝硬化门静脉高压食管胃底曲张静脉破裂大出血病人分为两组,分别用思他宁和垂体后叶素治疗,观察24 h止血率、总止血率、1周再出血率、1周死亡率和副反应发生率。结果 思他宁组24 h止血率和总止血率明显高于垂体后叶素组,1周再出血率、1周死亡率和副反应发生率明显低于垂体后叶素组。结论 思他宁用于治疗肝硬化门静脉高压食管胃底曲张静脉破裂大出血,止血效果确切,副作用少,明显优于垂体后叶素。 Objective To observe the effect of Stilamin in treating cirrhotic portal hypertensive esophageal varices bleeding, and compare with pituitrin. Methods Forty patients with portal hypertensive esophageal-gastric variceal bleeding were divided into two groups. The patients were treated with statin and pituitrin respectively. The rates of hemostasis, total bleeding, re-bleeding for 1 week, Weekly mortality and incidence of side effects. Results The rates of hemostasis and total hemostasis at the first 24 h in statin group were significantly higher than those in the pituitrin group. The rates of one-week rebleeding, 1-week mortality and side effects were significantly lower than those in the pituitrin group. Conclusion Stilamin for the treatment of cirrhotic portal hypertension with esophageal variceal bleeding, bleeding effect is exact, less side effects, significantly better than pituitrin.