沙利度胺(thalidomide)又名反应停、酞咪哌啶酮,最早作为镇静止吐药物使用,尤其用于孕妇镇吐,后来主要与抗麻疯病药联合使用,用于治疗各型麻风反应。近几年,沙利度胺被发现了一些药理学上的新特性,即具有免疫调节及抑制血管生成的作用,临床对于白塞氏病治疗有效。 Thalidomide, also known as thalidomide, thalidomide, was first used as a sedative and antiemetic drug, especially for antiemetic in pregnant women, and was later used primarily in combination with anti-leprosy drugs for the treatment of various forms of leprosy reaction. In recent years, thalidomide has been found in some pharmacological new features, that is, immune regulation and inhibition of angiogenesis, clinical treatment of Behcet’s disease is effective.