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目的 :揭示结核患者红细胞免疫功能的变化 ;方法 :应用补体致敏酵母菌血凝法检测结核患者与献血员的红细胞免疫粘附促进因子 (RFER)及免疫粘附抑制因子 (RFIR) ,从而评定细胞免疫粘附功能 ;结果 :检测 5 0例结核患者和 65例健康献血者后发现 ,结核患者、健康献血员的RFER分别为 85 .1 0 %± 2 9.5 8%和 1 61 .3 7%± 3 6.70 % ;RFIR为3 8.2 3 %± 1 0 .87%和 3 9.5 2 %± 1 3 .1 5 % ,结核患者的RFER明显低于献血员 (P <0 .0 1 ) ,而RPIR差异不显著 (P >0 .0 5 ) ;结核患者血凝滴度 1 8时阳性率为 6% ,健康献血员达44 .61 % ,有显著差异 (P >0 .0 1 ) ;结论 :结核患者与健康献血员红细胞免疫功能相比有显著变化 ,前者低于后者。
Objective: To reveal the changes of erythrocyte immune function in patients with tuberculosis. Methods: The erythrocyte immune adherence promoting factor (RFER) and immune adherence inhibitory factor (RFIR) of tuberculosis patients and blood donors were detected by complement-sensitized yeast hemagglutination. Results: 50 patients with tuberculosis and 65 healthy blood donors were detected. The RFER of tuberculosis patients and healthy blood donors were 85.1% ± 2 9.58% and 16.37% ± 3. 6.70%; RFIR was 3 8.23% ± 1.087% and 3 9.5 2% ± 1 3 .15% respectively. The RFER of tuberculosis patients was significantly lower than that of blood donors (P <0.01) The difference was not significant (P> 0.05). The positive rate of blood clotting titer was 18% in tuberculosis patients and 44.61% in healthy blood donors (P> 0.05). Conclusion: Tuberculosis patients and healthy blood donors compared to red blood cell immune function has significantly changed, the former is lower than the latter.