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本文集中分析研究了直肠癌的肿瘤生长方式的特征,其与诸病理学因素的关系,及不同生长方式对生存率的影响,研究结果表明:呈推进性生长者,由于其多为大的癌巢向周围推挤,周围有较多的纤维组织增生,限制肿瘤向周围扩散,因此它难于向纵横及深层浸润;而且其侵犯小静脉及小淋巴管的能力差;多表现为中、高分化腺癌,切除率及根切率高,患者5、10年的生存率亦高。而呈浸润性生长者则与此相反。作者认为生长方式在诸生物学特性中起着主导作用,并且对判定预后也有重要的意义。因而有必要深入对生长方式进行研究,并建议将生长方式作为病理诊断中的常规项目进行观察,可能对临床判定预后有指导意义。
This article focuses on the analysis of the characteristics of the tumor growth pattern of rectal cancer, its relationship with various pathological factors, and the effect of different growth patterns on the survival rate. The results of the study indicate that those who are advancing grow because they are mostly large cancers. The nest pushed around, there are more fibrous tissue around, limiting the spread of the tumor to the surrounding, so it is difficult to infiltrate into the vertical and horizontal and deep; and its ability to invade the small veins and small lymphatic vessels is poor; more manifested as moderately differentiated Adenocarcinomas have high rates of resection and excision, and patients have high 5-year and 10-year survival rates. The opposite is true for infiltrating growers. The author believes that the growth mode plays a leading role in various biological characteristics and is also of great significance in determining the prognosis. Therefore, it is necessary to study the growth pattern in depth, and it is suggested that the growth pattern be observed as a routine item in pathological diagnosis, which may be of guiding significance for clinical judgment of prognosis.