丹参新醌丁的分离与结构测定

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丹参(Salvia miltiorrhiza)中含量较高的是以邻醌为主如丹参酮Ⅰ及丹参酮Ⅱ_A等,而以对醌存在的尚有异丹参酮等,但含量均极低。此外,国内还报道了显示酸性的丹参新醌甲、乙,丙。鉴于隐丹参酮、二氢丹参酮Ⅰ加碱开环后可转化为丹参新醌,因此如不用碱处理能否从原植物中获得新醌尚属未定。本文报道采用中性溶剂系统进行硅胶柱层析,获得了丹参新醌甲与乙,此外还得到一种新的对醌化合物,不同于已报道的异丹参酮,定名为丹参新醌 The contents of Salvia miltiorrhiza are higher than that of o-quinones, such as tanshinone I and tanshinone II_A. However, there are still some iso-tanshinones, but the content is very low. In addition, domestically reported Salvia miltiorrhiza, B, and C that show acidity. Since cryptotanshinone and dihydrotanshinone I can be converted into salvia miltiorrhiza after ring-opening, it is still undecided whether or not it can be obtained from the original plant without alkali treatment. This paper reports the use of a neutral solvent system for silica gel column chromatography to obtain Salvia miltiorrhiza B and Salvia miltiorrhiza, in addition to a new paradoxime compound, which is different from the reported iso-tanshinone and named Salvia miltiorrhiza.
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