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自身免疫性甲状腺疾病(AITD)是一组病变部位为甲状腺的器官特异性自身免疫病,主要包括Graves病和桥本甲状腺炎,临床主要表现为甲状腺功能亢进或甲状腺功能低下。瘦素(LP)是一种主要由脂肪细胞合成分泌的蛋白类激素,是维持能量代谢平衡和脂肪容量的最重要的激素之一,参与机体能量的摄取、储存和释放,与许多内分泌代谢性疾病关系密切。本研究测定自身免疫性甲状腺疾病病人的瘦素表达,为临床及时用药干预提供新的方法。
Autoimmune thyroid disease (AITD) is a group of organ-specific autoimmune diseases with thyroid lesions, including Graves’ disease and Hashimoto’s thyroiditis. The main clinical manifestations are hyperthyroidism or hypothyroidism. Leptin (LP), a protein hormone secreted and synthesized mainly by adipocytes, is one of the most important hormones to maintain energy metabolism balance and fat volume. It is involved in the energy intake, storage and release of body energy, and many endocrine and metabolic The disease is closely related. This study determined the expression of leptin in patients with autoimmune thyroid disease, providing a new method for clinical intervention.