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目的观察干扰素在治疗毛细支气管炎中的临床疗效。方法将符合纳入标准的患儿88例随机分为观察组44例,对照组44例,单独使用利巴韦林,观察组在使用利巴韦林基础上加用干扰素,其用法100U/次,1次/d肌注,疗程3～5d,其他对症处理及支持疗法相同。结论观察组临床显效率、有效率、总有效率均高于对照组,差异有统计学意义(P<0.05)观察组未出现明显的副作用。结论故干扰素在治疗儿科毛细支气管炎疗效确切,安全性好,值得临床应用。
Objective To observe the clinical efficacy of interferon in the treatment of bronchiolitis. Methods Eighty-eight children who met the inclusion criteria were randomly divided into observation group (n = 44), control group (n = 44) and ribavirin alone. The observation group was given ribavirin plus interferon , 1 / d intramuscular injection, course of treatment 3 ~ 5d, other symptomatic treatment and supportive therapy the same. Conclusions The clinical effective rate, effective rate and total effective rate in the observation group were significantly higher than those in the control group (P <0.05). No obvious side effects were observed in the observation group. Conclusion Therefore interferon in the treatment of pediatric bronchiolitis is effective and safe, it is worth clinical application.