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目的:观察Ⅲ期非小细胞肺癌支气管动脉化疗加放疗与单纯放射治疗疗效。方法:随机选不宜手术治疗的Ⅲ期小细胞肺癌68例,41例行支气管动脉灌注化疗加放射治疗,另27例单用放射治疗,两组放疗方法和剂量相似,定期观察。结果:化疗加放疗组总有效率80.4％,完全缓解率21.9％,单纯放疗组总有效率44.4％,完全缓解率7.4％,卡方检验有显著性意义(P<0.05),中位生存期前者为16个月,后者8个月。结论:对不能手术的Ⅲ期非小细胞肺癌化疗加放疗的有效率增加,生存期明显延长。
Objective: To observe the effect of bronchial arterial chemo-radiotherapy plus radiotherapy alone in the treatment of stage III non-small cell lung cancer. Methods: Sixty-eight cases of stage III small cell lung cancer that were not suitable for surgery were randomized. Forty-one cases were treated with bronchial arterial infusion chemotherapy plus radiotherapy. The other 27 cases were treated with radiation alone. The radiotherapy methods and doses of the two groups were similar and were regularly observed. Results: The total effective rate of chemotherapy plus radiotherapy group was 80.4%, the complete remission rate was 21.9%, the total effective rate of radiotherapy alone group was 44.4%, and the complete remission rate was 7.4%. The chi-square test had significant significance (P<0.05). The former is 16 months and the latter is 8 months. Conclusion: The effective rate of chemotherapy and radiotherapy for non-surgical stage III non-small cell lung cancer is increased, and the survival period is prolonged.