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目的探讨新生儿重症监护中心感染菌群分布特征及相关因素。方法选取该院2012年3月-2013年9月新生儿重症监护病房院内感染患儿48例,对其进行细菌培养、药敏试验,分析其感染菌群分布特征及相关因素。结果引发院内感染因素有气管插管、其他侵入性操作、极低体质量儿、基础疾病、医源性传播。69株病原菌中有革兰氏阴性杆菌56株,革兰氏阳性球菌13株,主要耐药性药物为氨苄西林、头孢唑啉等,敏感率较高的为万古霉素、亚胺培南、哌拉西林。结论根据感染相关高危因素,提高新生儿重症监护中心预防管理水平,减少感染发生率。
Objective To investigate the distribution characteristics of infection flora in neonatal intensive care center and related factors. Methods Forty eight infants with nosocomial infection in neonatal intensive care unit from March 2012 to September 2013 in our hospital were selected for bacterial culture and drug susceptibility testing. The distribution characteristics and related factors of the infected bacteria were analyzed. The results lead to nosocomial infections tracheal intubation, other invasive procedures, very low birth weight children, basic diseases, iatrogenic transmission. Among the 69 pathogens, 56 were Gram-negative bacilli and 13 were Gram-positive cocci. The main drug-resistant drugs were ampicillin, cefazolin, etc. The most sensitive ones were vancomycin, imipenem, Piperacillin. Conclusion According to the infection-related risk factors, we can improve the prevention and management of neonatal ICU and reduce the incidence of infection.