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无菌性脑膜炎是由許多非細菌性病原所引起的綜合征。1925年Wallgren氏首先提出的診断标准为:①急性起病而伴有脑膜刺激征;②脑脊髓液細胞增多,尤以单核細胞为著;③脑脊髓液细菌培养阴性;④病程較短而无合併症且能完全恢复;⑤缺乏脑膜附近感染病灶如中耳炎、鼻竇炎及外伤,也不是全身感染过程中继发的脑膜炎;⑥在当时当地沒有中樞神經系統感染的流行。到目前为止,除第6条因近年发現引起无菌性脑膜炎的腸道病毒本身可以引起流行而需加以修訂外,大致上尚可适用。
Aseptic meningitis is a syndrome caused by many non-bacterial pathogens. 1925 Wallgren’s first proposed diagnostic criteria: ① acute onset associated with meningeal irritation; ② increased cerebrospinal fluid cells, monocytes; ③ cerebrospinal fluid bacterial culture; ④ shorter duration No complications and can fully recover; ⑤ lack of lesions near the meninges such as otitis media, sinusitis and trauma, is not secondary to meningitis during systemic infection; ⑥ there was no central nervous system infection prevalence. So far, it has generally been applicable except Article 6, which has to be revised in view of the fact that enterovirus causing aseptic meningitis has itself been found to be epidemic in recent years.