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促性腺激素和垂体分泌的其他激素以波动的形式释放,已得到广泛承认。据观察,猴子LH的波动频率是每60分钟1次,包括人在内的许多哺乳动物血浆中LH波动也具有规律。间歇的LH释放似乎是由于LHRH波动的排放到垂体门脉血中的结果。这种推测得到几方面研究结果的支持。其一,在猴子几种α-肾上腺素能阻断剂能阻止其LH的波动释放;其二,垂体柄中LHRH的浓度呈波动状并与LH波动频率一致;而且,下丘脑中基底部神经活动的电描记也提示:在切除了卵巢的猴子,电活动与LHRH释放的波动模式之间有一定关系。神经冲动大约间隔1小时出现1次,它可能控制着
Gonadotropins and other hormones secreted by the pituitary in a volatile form of release, has been widely recognized. It has been observed that the frequency of fluctuations in the monkey LH is once every 60 minutes, and the LH fluctuations in the plasma of many mammals, including humans, are also regular. Intermittent LH release appears to be the result of the release of fluctuating LHRH into the pituitary portal blood. This speculation is supported by several studies. First, several alpha-adrenergic blockers in monkeys can prevent the release of their LH fluctuations; second, the concentration of LHRH in the pituitary stalk fluctuates and is consistent with the frequency of LH fluctuations; and the basal ganglia in the hypothalamus The electrogram of the activity also suggested that there was a relationship between electrical activity and the pattern of fluctuations in LHRH release in ovariectomized monkeys. Nerve impulses occur about 1 hour apart, and it may take control