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科学家在对小鼠的研究中发现,骨质疏松症与炎症性肠道疾病都是由于机体内一种常见蛋白质异常造成的。来自英格兰 Leeds 大学的 Simon R.Carding 等人在今年12月份的《免疫学》杂志上发表了他们的研究结果。研究人员报告说:“自家免疫性骨质疾病和肠道炎症性疾病与 CD4T 细胞失常和活性过高密切相关,这两种变化都与机体的防御系统和免疫反应有关。但是这些 T 细胞是如何被激活的,以及如何介导疾病发生目前尚不清楚。”科学家解释说,小鼠经过基因改造后体内缺乏 CD4T 细胞关键调节因子,由
In a study of mice, scientists found that both osteoporosis and inflammatory bowel disease are caused by a common protein abnormality in the body. Simon R. Carding and others from Leeds University in England published their findings in the December issue of Immunology. The researchers report: “Autoimmune bone disease and inflammatory bowel disease are closely linked to abnormal CD4 T cell activity and hyperactivity, both of which are related to the body’s defense system and immune response, but how these T cells are Is activated, and how to mediate the disease is not yet clear. ”Scientists explained that mice after genetically modified lack of key regulatory factors CD4T cells, from