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目的通过探讨18F-氟代脱氧葡萄糖(18F-FDG)正电子发射断层扫描/电子计算机体层成像(PET/CT)误诊肺部占位性病变的原因。方法分析新疆自治区人民医院6年中924例肺部占位性病变患者行18F-FDG PET/CT检查诊断为肿瘤或者良性病变,其中有28例患者通过组织学或者病理学等检查后发现均为误诊病例。结果在28例患者中有6例为18F-FDGPET/CT误诊为阴性,通过活检病理确诊为恶性肿瘤;22例18F-FDG PET/CT误诊为阳性,通过活检病理或者细菌学检查确诊为良性病变,并在随访后得到证实。结论随18F-FDG PET/CT检查的流行,在临床上对于该检查的假阳性率及假阴性率也逐渐被认识,如果联合血肿瘤标记物的检查及对病例病史特点的详细分析可减少误诊率。
Objective To investigate the causes of misdiagnosis of pulmonary space occupying lesions by 18F-FDG PET / CT scan. Methods A total of 924 patients with lung-space occupying lesions in People’s Hospital of Xinjiang Uygur Autonomous Region were diagnosed as tumor or benign lesions by 18F-FDG PET / CT. Sixteen of them were found by histological examination or pathological examination Misdiagnosed cases. Results Of the 28 patients, 6 cases were misdiagnosed as negative by 18F-FDG PET / CT and were diagnosed as malignant tumors by biopsy. Twenty-two cases of 18F-FDG PET / CT were misdiagnosed as positive and confirmed by biopsy or bacteriological examination as benign lesions , And confirmed after follow-up. Conclusions With the prevalence of 18F-FDG PET / CT examination, the false positive rate and false negative rate of this examination are also gradually recognized. If combined with the examination of blood tumor markers and the detailed analysis of the characteristics of the case history can reduce the misdiagnosis rate.