自体外周血干细胞移植是难治及复发多发性骨髓瘤的补救治疗，临床应用具有较好的疗效。本文报道用其治疗多发性骨髓瘤１例。患者，女，３７岁。因“乏力半年，发热１个月”入院。查体：Ｔ３７８℃，贫血貌，浅表淋巴结不大。心肺正常，肝脾不大。全身骨无压痛。血常规：Ｈｂ Autologous peripheral blood stem cell transplantation is a salvage treatment for refractory and relapsed multiple myeloma, and clinical application has a good effect. This article reports one case of multiple myeloma treated with it. Patient, female, 37 years old. He was admitted to hospital because of “fatigue for six months and fever for one month.” Physical examination: T378°C, anemia appearance, superficial lymph nodes are not large. Normal heart and lung, liver and spleen is not. Whole body bone without tenderness. Blood routine: Hb