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从肝癌高发区——扶绥县主粮中分离的污染真菌,在大米——玉米培养基上培养,其培养物的提取液用SCE实验来检测。供试菌有100株,结果有10株为阳性。(即杂色曲霉菌的全部,3/6的棕曲霉菌以及2/5的构巢曲霉)与Ames法实验结果相吻合。提示在霉变的粮食里存在着致突变的物质,可能在肝癌的发生中起重要的作用。因此,不但要预防黄曲霉菌的污染,还要预防其他霉菌的污染,这可能是降低肝癌发病率的重要措施之一。
The contaminating fungi isolated from the main grain of Fusui County, a high-risk area of liver cancer, were cultured on a rice-corn culture medium. The extract of the culture was detected by SCE. There were 100 strains of bacteria tested and 10 strains were positive. (ie, all Aspergillus versicolor, 3/6 Aspergillus flavus, and 2/5 Aspergillus nidulans) were consistent with the Ames test results. It suggests that there is a mutagenic substance in the mildewed food that may play an important role in the occurrence of liver cancer. Therefore, we must not only prevent the contamination of Aspergillus flavus, but also prevent the contamination of other molds, which may be one of the important measures to reduce the incidence of liver cancer.