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目的 探讨原发性鼻腔非霍奇金淋巴瘤 (NHL)的临床和病理特征。方法 对 17例患者的临床资料进行回顾性分析。结果 17例鼻腔NHL中 ,NK/T细胞淋巴瘤 9例 ,外周T细胞淋巴瘤 6例 ,B细胞淋巴瘤 2例。NK/T细胞淋巴瘤可见血管中心、血管浸润及坏死现象 ,外周T细胞淋巴瘤和B细胞淋巴瘤中未见。NK/T细胞淋巴瘤 9例全部死亡 ,外周T细胞淋巴瘤 6例中 4例生存 ,B细胞淋巴瘤 2例均生存。结论 原发性鼻腔NHL多发生于男性 ;NK/T细胞淋巴瘤较多见 ,具有较高的侵袭性和恶性度 ,预后更差。
Objective To investigate the clinical and pathological features of primary nasal non-Hodgkin’s lymphoma (NHL). Methods The clinical data of 17 patients were retrospectively analyzed. Results Of the 17 cases of nasal NHL, 9 were NK / T cell lymphoma, 6 were peripheral T-cell lymphoma and 2 were B-cell lymphoma. NK / T cell lymphoma visible vascular center, vascular invasion and necrosis, peripheral T cell lymphoma and B cell lymphoma was not seen. All 9 NK / T cell lymphomas were dead, 4 of 6 peripheral T cell lymphoma survived and 2 of B cell lymphoma survived. Conclusions Primary nasal NHL mostly occurs in men. NK / T cell lymphoma is more common, with higher invasiveness and malignancy, and worse prognosis.