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目的 比较舒喘宁定量气雾剂 (MDI)与液剂雾化吸入在儿童哮喘急性发作中的疗效及副作用。方法 将儿童哮喘轻 -中度发作 68例随机分为两组 :1组 (MDI组 ) 3 6例 ,使用潴雾罐辅助喘乐宁定量气雾剂吸入治疗 ;2组 (雾化吸入组 ) 3 2例 ,使用 0 5 %舒喘宁液剂雾化吸入治疗。 60min后评价临床疗效 ,观察治疗前后呼吸频率、最大呼气峰流速(PEF)占预计值的百分比的变化。结果 1,2组在上述指标差异无显著性 ,2组治疗后心率改变量显著高于 1组。结论 舒喘宁定量气雾剂与液剂雾化吸入治疗儿童轻 -中度哮喘发作疗效相近 ,雾化剂有使心率增快的副作用。
Objective To compare the curative effect and side effects of salbutamol quantitative aerosol (MDI) and liquid atomizing inhalation in children with acute exacerbation of asthma. Methods Sixty-six children with mild to moderate childhood asthma were randomly divided into two groups: group 1 (MDI group), 36 cases, which were treated with buprenorphine aerosol inhalation therapy; group 2 (aerosol inhalation group) 32 cases were treated with 0 5% salbutamol solution atomized inhalation. After 60 minutes, the clinical efficacy was evaluated. The changes of respiratory rate and maximum expiratory flow rate (PEF) before and after treatment were observed. Results There was no significant difference between the two groups in the above indexes. The changes of heart rate in the two groups after treatment were significantly higher than those in the first group. CONCLUSIONS: Salbutamol dose aerosol inhalation is effective in treating children with mild-moderate asthma attack. The nebulizer has the side effect of increasing heart rate.