脑肿瘤的年发病率和死亡率在国内还没有精确的统计数字,美国统计数据表明每年大约有20 000例原发性及200 000例转移性脑肿瘤新发病例[1]。全球范围的脑肿瘤患者更是难以计数,即使经过手术切除,脑肿瘤极高的复发率严重影响患者生活质量。此外,由于抗癌药物很难通过血脑屏障,传统 The annual incidence and mortality of brain tumors do not have accurate statistics in China. According to the statistics of the United States, there are about 20,000 new cases of primary and 200,000 cases of metastatic brain tumors each year [1]. Patients with brain tumors worldwide are even more difficult to count. Even after surgical resection, the high recurrence rate of brain tumors seriously affects the quality of life of patients. In addition, since anti-cancer drugs are difficult to pass through the blood-brain barrier, traditionally