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最近报道芬氟拉明(fenfluramine)与芬特明(phentermine)两种食欲抑制剂合用引起心瓣膜疾病的危险性增加,特别是主动脉瓣与僧帽瓣功能不全发病率增加。研究表明单用芬氟拉明或右芬氟拉明(dexfenfluramine)3个月以上亦可致心瓣膜疾病发生。为阐明3种药物与心瓣膜疾病的相关?..
Recently, the combination of fenfluramine and phentermine has been reported to increase the risk of valvular heart disease, especially the aortic valve and mitral valve insufficiency. Studies have shown that single-use fenfluramine or dexfenfluramine (dexfenfluramine) more than 3 months can also cause heart valve disease. To clarify the three drugs associated with heart valve disease? ..