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Infect Dis J.- 1 999,1 8(7) .- 6 2 4～ 6 30 在成人、学龄儿童 (5～ 9岁 )及学龄前儿童 (2 4～ 5 9月龄 )中 ,口服霍乱活菌苗CVD1 0 3- Hg R〔剂量为 5× 1 0 9集落形成单位(CFU)〕有很好的耐受性和免疫原性。为了研究婴幼儿 (3～ 1 7月龄 )对此菌苗的临床可接受性、免疫
Infect Dis J.- 1 999,1 8 (7) .- 6 2 4 ~ 6 30 Cholera was administered orally in adults, school-age children (5 to 9 years) and preschool children (24 to 59 months) The vaccine (5x109 CFU) is well tolerated and immunogenic. To study the clinical acceptability of this vaccine in infants and young children (3 to 17 months of age), immunization was performed